EBI3 anticorps (C-Term)

N° du produit ABIN1881277

Cet anticorps Lapin Polyclonal détecte spécifiquement EBI3 dans WB. Il présente une réactivité envers Humain et a été mentionné dans 4+ publications.

Aperçu rapide pour EBI3 anticorps (C-Term) (ABIN1881277)

Antigène: EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EBI3 est non-conjugé

Application: Western Blotting (WB)

Clone: RB30602

Détail du produit anti-EBI3 anticorps

Épitope: AA 153-181, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This EBI3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-181 amino acids from the C-terminal region of human EBI3.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-EBI3 (ABIN1881277)

Kempe, Heinz, Kokai, Devergne, Marx, Wirth: "Epstein-barr virus-induced gene-3 is expressed in human atheroma plaques." dans: The American journal of pathology, Vol. 175, Issue 1, pp. 440-7, (2009) (PubMed).

Krumbiegel, Anthogalidis-Voss, Markus, Zepp, Meyer: "Enhanced expression of IL-27 mRNA in human newborns." dans: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, Vol. 19, Issue 6, pp. 513-6, (2008) (PubMed).

Poleganov, Bachmann, Pfeilschifter, Mühl: "Genome-wide analysis displays marked induction of EBI3/IL-27B in IL-18-activated AML-derived KG1 cells: critical role of two kappaB binding sites in the human EBI3 promotor." dans: Molecular immunology, Vol. 45, Issue 10, pp. 2869-80, (2008) (PubMed).

Carl, Bai: "IL27: its roles in the induction and inhibition of inflammation." dans: International journal of clinical and experimental pathology, Vol. 1, Issue 2, pp. 117-23, (2008) (PubMed).

Détails sur EBI3

Antigène: EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))

Autre désignation: EBI3

Sujet: This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.

Poids moléculaire: 25396

NCBI Accession: NP_005746

UniProt: Q14213