EBI3 anticorps (C-Term)
Aperçu rapide pour EBI3 anticorps (C-Term) (ABIN1881277)
Antigène
Voir toutes EBI3 (IL-27b) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 153-181, C-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This EBI3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-181 amino acids from the C-terminal region of human EBI3.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Date de péremption
- 6 months
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: "Epstein-barr virus-induced gene-3 is expressed in human atheroma plaques." dans: The American journal of pathology, Vol. 175, Issue 1, pp. 440-7, (2009) (PubMed).
: "Enhanced expression of IL-27 mRNA in human newborns." dans: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, Vol. 19, Issue 6, pp. 513-6, (2008) (PubMed).
: "Genome-wide analysis displays marked induction of EBI3/IL-27B in IL-18-activated AML-derived KG1 cells: critical role of two kappaB binding sites in the human EBI3 promotor." dans: Molecular immunology, Vol. 45, Issue 10, pp. 2869-80, (2008) (PubMed).
: "IL27: its roles in the induction and inhibition of inflammation." dans: International journal of clinical and experimental pathology, Vol. 1, Issue 2, pp. 117-23, (2008) (PubMed).
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- EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))
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Autre désignation
- EBI3
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Sujet
- This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.
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Poids moléculaire
- 25396
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NCBI Accession
- NP_005746
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UniProt
- Q14213
Antigène
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