ESR2 anticorps (AA 211-240)

N° du produit ABIN1881322

Cet anticorps Lapin Polyclonal détecte spécifiquement ESR2 dans WB. Il présente une réactivité envers Humain et Souris et a été mentionné dans 2+ publications.

Aperçu rapide pour ESR2 anticorps (AA 211-240) (ABIN1881322)

Antigène: ESR2 (Estrogen Receptor 2 (ESR2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ESR2 est non-conjugé

Application: Western Blotting (WB)

Clone: RB41114

Détail du produit anti-ESR2 anticorps

Épitope: AA 211-240

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ESR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-240 amino acids from the Central region of human ESR2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ESR2 (ABIN1881322)

Fang, Lu, Wang, Wu, Li, Zhang, Pan, Wan: "Prognostic impact of ERβ and MMP7 expression on overall survival in colon cancer." dans: Tumour biology, Vol. 31, Issue 6, pp. 651-8, (2010) (PubMed).

Hayes, Skaar, Rae, Henry, Nguyen, Stearns, Li, Philips, Desta, Flockhart: "Estrogen receptor genotypes, menopausal status, and the effects of tamoxifen on lipid levels: revised and updated results." dans: Clinical pharmacology and therapeutics, Vol. 88, Issue 5, pp. 626-9, (2010) (PubMed).

Détails sur ESR2

Antigène: ESR2 (Estrogen Receptor 2 (ESR2))

Autre désignation: ESR2

Sujet: This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.

Poids moléculaire: 59216

NCBI Accession: NP_001035365, NP_001201831, NP_001201832, NP_001258805, NP_001258806, NP_001428

UniProt: Q92731

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling