FCRL3 anticorps (C-Term)

N° du produit ABIN1881343

Détail du produit anti-FCRL3 anticorps

Antigène: FCRL3 (Fc Receptor-Like 3 (FCRL3))

Épitope: AA 694-720, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FCRL3 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This FCRL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 694-720 amino acids from the C-terminal region of human FCRL3.

Clone: RB41960

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-FCRL3 (ABIN1881343)

Swainson, Mold, Bajpai, McCune: "Expression of the autoimmune susceptibility gene FcRL3 on human regulatory T cells is associated with dysfunction and high levels of programmed cell death-1." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 7, pp. 3639-47, (2010) (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." dans: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Zheng, Zhao, Zhang, Li: "[Study on the association of 3 SNPs of FcRL3 gene with Graves disease in Chongqing Han population]." dans: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, Vol. 26, Issue 6, pp. 681-5, (2009) (PubMed).

Gibson, Li, Wu, Edberg, Su, Cafardi, Wiener, Tiwari, Kimberly, Davis: "The FCRL3-169CT promoter single-nucleotide polymorphism, which is associated with systemic lupus erythematosus in a Japanese population, predicts expression of receptor protein on CD19+ B cells." dans: Arthritis and rheumatism, Vol. 60, Issue 11, pp. 3510-2, (2009) (PubMed).

Détails sur FCRL3

Antigène: FCRL3 (Fc Receptor-Like 3 (FCRL3))

Autre désignation: FCRL3 (FCRL3 Produits)

Sujet: This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus.

Poids moléculaire: 80856

NCBI Accession: NP_443171

UniProt: Q96P31