GAR1 anticorps (AA 86-114)

N° du produit ABIN1881363

Cité dans 3 publications. Cet anticorps anti-GAR1 Polyclonal Lapin (Clone RB39831) (ABIN1881363) détecte spécifiquement GAR1 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour GAR1 anticorps (AA 86-114) (ABIN1881363)

Antigène: GAR1 (GAR1 Ribonucleoprotein Homolog (Yeast) (GAR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAR1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB39831

Détail du produit anti-GAR1 anticorps

Épitope: AA 86-114

Homologie: Zf, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GAR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human GAR1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-GAR1 (ABIN1881363)

Hamma, Ferré-DAmaré: "The box H/ACA ribonucleoprotein complex: interplay of RNA and protein structures in post-transcriptional RNA modification." dans: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 805-9, (2010) (PubMed).

Kalsi, Kuo, Aliev, Alexander, McMichael, Patterson, Walsh, Zhao, Schuckit, Nurnberger, Edenberg, Kramer, Hesselbrock, Tischfield, Vladimirov, Prescott, Dick, Kendler, Riley: "A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts." dans: Human molecular genetics, Vol. 19, Issue 12, pp. 2497-506, (2010) (PubMed).

Pigullo, Pavesi, Dianzani, Santamaria, Svahn, Risso, Van Lint, Pillon, Iori, Longoni, Ramenghi, Lanciotti, Dufour: "NOLA1 gene mutations in acquired aplastic anemia." dans: Pediatric blood & cancer, Vol. 52, Issue 3, pp. 376-8, (2009) (PubMed).

Détails sur GAR1

Antigène: GAR1 (GAR1 Ribonucleoprotein Homolog (Yeast) (GAR1))

Autre désignation: GAR1

Sujet: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p. Two splice variants have been found for this gene.

Poids moléculaire: 22348

NCBI Accession: NP_061856, NP_127460

UniProt: Q9NY12