GLUD2 anticorps (N-Term)

N° du produit ABIN1881376

Cet anticorps Lapin Polyclonal détecte spécifiquement GLUD2 dans WB. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour GLUD2 anticorps (N-Term) (ABIN1881376)

Antigène: GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLUD2 est non-conjugé

Application: Western Blotting (WB)

Clone: RB42527

Détail du produit anti-GLUD2 anticorps

Épitope: AA 75-103, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GLUD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-103 amino acids from the N-terminal region of human GLUD2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-GLUD2 (ABIN1881376)

Spanaki, Zaganas, Kleopa, Plaitakis: "Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular supporting cells." dans: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16748-56, (2010) (PubMed).

Plaitakis, Latsoudis, Kanavouras, Ritz, Bronstein, Skoula, Mastorodemos, Papapetropoulos, Borompokas, Zaganas, Xiromerisiou, Hadjigeorgiou, Spanaki: "Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset." dans: European journal of human genetics : EJHG, Vol. 18, Issue 3, pp. 336-41, (2010) (PubMed).

Détails sur GLUD2

Antigène: GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))

Autre désignation: GLUD2

Sujet: The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.

Poids moléculaire: 61434

NCBI Accession: NP_036216

UniProt: P49448

Pathways: Synaptic Membrane