Granulin anticorps (C-Term)

N° du produit ABIN1881391

Cet anticorps Lapin Polyclonal détecte spécifiquement Granulin dans WB et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour Granulin anticorps (C-Term) (ABIN1881391)

Antigène: Granulin (GRN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Granulin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB44397

Détail du produit anti-Granulin anticorps

Épitope: AA 563-591, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 563-591 amino acids from the C-terminal region of human GRN.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-Granulin (ABIN1881391)

Bhandari, Bateman: "Structure and chromosomal location of the human granulin gene." dans: Biochemical and biophysical research communications, Vol. 188, Issue 1, pp. 57-63, (1992) (PubMed).

Plowman, Green, Neubauer, Buckley, McDonald, Todaro, Shoyab: "The epithelin precursor encodes two proteins with opposing activities on epithelial cell growth." dans: The Journal of biological chemistry, Vol. 267, Issue 18, pp. 13073-8, (1992) (PubMed).

Bhandari, Palfree, Bateman: "Isolation and sequence of the granulin precursor cDNA from human bone marrow reveals tandem cysteine-rich granulin domains." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 5, pp. 1715-9, (1992) (PubMed).

Détails sur Granulin

Antigène: Granulin (GRN)

Autre désignation: GRN

Sujet: Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth.

Poids moléculaire: 63544

NCBI Accession: NP_002078

UniProt: P28799