HIST2H2AC anticorps (AA 18-46)

N° du produit ABIN1881417

Cité dans 3 publications. Cet anticorps anti-HIST2H2AC Polyclonal Lapin (Clone RB41799) (ABIN1881417) détecte spécifiquement HIST2H2AC dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour HIST2H2AC anticorps (AA 18-46) (ABIN1881417)

Antigène: HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIST2H2AC est non-conjugé

Application: Western Blotting (WB)

Clone: RB41799

Détail du produit anti-HIST2H2AC anticorps

Épitope: AA 18-46

Homologie: Rat, B, X, M, C, Pr, Zf, D

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-HIST2H2AC (ABIN1881417)

Ishibashi, Dryhurst, Rose, Shabanowitz, Hunt, Ausió: "Acetylation of vertebrate H2A.Z and its effect on the structure of the nucleosome." dans: Biochemistry, Vol. 48, Issue 22, pp. 5007-17, (2009) (PubMed).

Karaczyn, Cheng, Buzard, Hartley, Esposito, Kasprzak: "Truncation of histone H2A's C-terminal tail, as is typical for Ni(II)-assisted specific peptide bond hydrolysis, has gene expression altering effects." dans: Annals of clinical and laboratory science, Vol. 39, Issue 3, pp. 251-62, (2009) (PubMed).

Zhao, Lang, Ito, Bonnet, Metzger, Sawatsubashi, Suzuki, Le Guezennec, Stunnenberg, Krasnov, Georgieva, Schüle, Takeyama, Kato, Tora, Devys: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." dans: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).

Détails sur HIST2H2AC

Antigène: HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))

Autre désignation: HIST2H2AC

Sujet: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.

Poids moléculaire: 13988

NCBI Accession: NP_003508

UniProt: Q16777