HNRNPH1 anticorps (N-Term)

N° du produit ABIN1881424

Cet anticorps Lapin Polyclonal détecte spécifiquement HNRNPH1 dans WB. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour HNRNPH1 anticorps (N-Term) (ABIN1881424)

Antigène: HNRNPH1 (Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNRNPH1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB42336

Détail du produit anti-HNRNPH1 anticorps

Épitope: AA 48-77, N-Term

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HNRNPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human HNRNPH1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-HNRNPH1 (ABIN1881424)

Van Dusen, Yee, McNally, McNally: "A glycine-rich domain of hnRNP H/F promotes nucleocytoplasmic shuttling and nuclear import through an interaction with transportin 1." dans: Molecular and cellular biology, Vol. 30, Issue 10, pp. 2552-62, (2010) (PubMed).

Rauch, ONeill, Mack, Matthias, Munz, Kolch, Gires: "Heterogeneous nuclear ribonucleoprotein H blocks MST2-mediated apoptosis in cancer cells by regulating A-Raf transcription." dans: Cancer research, Vol. 70, Issue 4, pp. 1679-88, (2010) (PubMed).

Fisette, Toutant, Dugré-Brisson, Desgroseillers, Chabot: "hnRNP A1 and hnRNP H can collaborate to modulate 5' splice site selection." dans: RNA (New York, N.Y.), Vol. 16, Issue 1, pp. 228-38, (2009) (PubMed).

Détails sur HNRNPH1

Antigène: HNRNPH1 (Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1))

Autre désignation: HNRNPH1

Sujet: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype. [provided by RefSeq].

Poids moléculaire: 49229

NCBI Accession: NP_001244222, NP_005511

UniProt: P31943