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ICT1 anticorps (C-Term)

Cet anticorps anti-ICT1 est un anticorps Lapin Polyclonal détectant ICT1 dans WB et IHC (p). Adapté pour Humain. Ce Primary Antibody a été cité dans 5+ publications.
N° du produit ABIN1881444

Aperçu rapide pour ICT1 anticorps (C-Term) (ABIN1881444)

Antigène

Voir toutes ICT1 Anticorps
ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))

Reactivité

  • 35
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 27
  • 8
Lapin

Clonalité

  • 29
  • 6
Polyclonal

Conjugué

  • 19
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ICT1 est non-conjugé

Application

  • 32
  • 13
  • 13
  • 11
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB42881
  • Épitope

    • 15
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 153-179, C-Term

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This ICT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-179 amino acids from the C-terminal region of human ICT1.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Date de péremption

    6 months
  • Wang, He, Zhang, Yang, Wang, Liu, Wu: "Knockdown of Immature Colon Carcinoma Transcript 1 Inhibits Proliferation and Promotes Apoptosis of Non-Small Cell Lung Cancer Cells." dans: Technology in cancer research & treatment, Vol. 16, Issue 5, pp. 559-569, (2018) (PubMed).

    Tao, Song, Han, Wang, Zhao, Gu: "miR-205 regulation of ICT1 has an oncogenic potential via promoting the migration and invasion of gastric cancer cells." dans: Biomedicine & pharmacotherapy, Vol. 96, pp. 191-197, (2018) (PubMed).

    Wang, Jin, Wu, Wang, Li: "Immature colon carcinoma transcript-1 promotes proliferation of gastric cancer cells." dans: Acta biochimica et biophysica Sinica, Vol. 49, Issue 11, pp. 979-988, (2018) (PubMed).

    Chang, Yu, Tian, Lin: "Immature colon carcinoma transcript-1 promotes cell growth of hepatocellular carcinoma via facilitating cell cycle progression and apoptosis resistance." dans: Oncology reports, Vol. 38, Issue 6, pp. 3489-3496, (2018) (PubMed).

    Xie, Zhang, Shen, Cao, Gu, Che: "Knockdown of immature colon carcinoma transcript-1 inhibits proliferation of glioblastoma multiforme cells through Gap 2/mitotic phase arrest." dans: OncoTargets and therapy, Vol. 8, pp. 1119-27, (2015) (PubMed).

  • Antigène

    ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))

    Autre désignation

    ICT1

    Sujet

    Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.

    Poids moléculaire

    23630

    NCBI Accession

    NP_001536

    UniProt

    Q14197
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