ILKAP anticorps (AA 93-122)

N° du produit ABIN1881459

Cité dans 3 publications. Cet anticorps anti-ILKAP Polyclonal Lapin (Clone RB40435) (ABIN1881459) détecte spécifiquement ILKAP dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ILKAP anticorps (AA 93-122) (ABIN1881459)

Antigène: ILKAP (Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C (ILKAP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ILKAP est non-conjugé

Application: Western Blotting (WB)

Clone: RB40435

Détail du produit anti-ILKAP anticorps

Épitope: AA 93-122

Homologie: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ILKAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the Central region of human ILKAP.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ILKAP (ABIN1881459)

Nakrieko, Vespa, Mason, Irvine, DSouza, Dagnino: "Modulation of integrin-linked kinase nucleo-cytoplasmic shuttling by ILKAP and CRM1." dans: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 14, pp. 2157-66, (2008) (PubMed).

Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." dans: Nature, Vol. 434, Issue 7034, pp. 724-31, (2005) (PubMed).

Kumar, Naruszewicz, Wang, Leung-Hagesteijn, Hannigan: "ILKAP regulates ILK signaling and inhibits anchorage-independent growth." dans: Oncogene, Vol. 23, Issue 19, pp. 3454-61, (2004) (PubMed).

Détails sur ILKAP

Antigène: ILKAP (Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C (ILKAP))

Autre désignation: ILKAP

Sujet: The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.

Poids moléculaire: 42907

NCBI Accession: NP_110395

UniProt: Q9H0C8