LHX4 anticorps (AA 133-161)

N° du produit ABIN1881496

Cet anticorps Lapin Polyclonal détecte spécifiquement LHX4 dans WB. Il présente une réactivité envers Humain et a été mentionné dans 4+ publications.

Aperçu rapide pour LHX4 anticorps (AA 133-161) (ABIN1881496)

Antigène: LHX4 (LIM Homeobox 4 (LHX4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LHX4 est non-conjugé

Application: Western Blotting (WB)

Clone: RB30670

Détail du produit anti-LHX4 anticorps

Épitope: AA 133-161

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This LHX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-161 amino acids from the Central region of human LHX4.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-LHX4 (ABIN1881496)

Castinetti, Saveanu, Reynaud, Quentien, Buffin, Brauner, Kaffel, Albarel, Guedj, El Kholy, Amin, Enjalbert, Barlier, Brue: "A novel dysfunctional LHX4 mutation with high phenotypical variability in patients with hypopituitarism." dans: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 7, pp. 2790-9, (2008) (PubMed).

de Bruijn, van Dijk, Willemse, van Kessel: "The C terminus of the synovial sarcoma-associated SSX proteins interacts with the LIM homeobox protein LHX4." dans: Oncogene, Vol. 27, Issue 5, pp. 653-62, (2008) (PubMed).

Pfaeffle, Hunter, Savage, Duran-Prado, Mullen, Neeb, Eiholzer, Hesse, Haddad, Stobbe, Blum, Weigel, Rhodes: "Three novel missense mutations within the LHX4 gene are associated with variable pituitary hormone deficiencies." dans: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 3, pp. 1062-71, (2008) (PubMed).

Liu, Luo, Liu, McNeilly, Cui: "Specificity protein 1 (Sp1) plays role in regulating LIM homeodomain transcription factor Lhx4 gene expression." dans: Biochemical and biophysical research communications, Vol. 366, Issue 1, pp. 36-41, (2007) (PubMed).

Détails sur LHX4

Antigène: LHX4 (LIM Homeobox 4 (LHX4))

Autre désignation: LHX4

Sujet: This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of the pituitary gland. Mutations in this gene are associated with syndromic short stature and pituitary and hindbrain defects. An alternative splice variant has been described but its biological nature has not been determined.

Poids moléculaire: 43124

NCBI Accession: NP_203129

UniProt: Q969G2