MEFV anticorps (AA 418-445)

N° du produit ABIN1881537

Détail du produit anti-MEFV anticorps

Antigène: MEFV (Mediterranean Fever (MEFV))

Épitope: AA 418-445

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEFV est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MEFV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418-445 amino acids from the Central region of human MEFV.

Clone: RB41739

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-MEFV (ABIN1881537)

Cosan, Ustek, Oku, Duymaz-Tozkir, Cakiris, Abaci, Ocal, Aral, Gül: "Association of familial Mediterranean fever-related MEFV variations with ankylosing spondylitis." dans: Arthritis and rheumatism, Vol. 62, Issue 11, pp. 3232-6, (2010) (PubMed).

He, Lu, Kang, Luan, Liu, Yin, Yao, Ding, Li, Heng: "MEFV E148Q polymorphism is associated with Henoch-Schönlein purpura in Chinese children." dans: Pediatric nephrology (Berlin, Germany), Vol. 25, Issue 10, pp. 2077-82, (2010) (PubMed).

Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." dans: Human genetics, Vol. 128, Issue 4, pp. 433-41, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Détails sur MEFV

Antigène: MEFV (Mediterranean Fever (MEFV))

Autre désignation: MEFV (MEFV Produits)

Synonymes: anticorps pyrin, anticorps MEFV, anticorps FMF, anticorps MEF, anticorps TRIM20, anticorps rfp domain, anticorps MEFV, pyrin innate immunity regulator, anticorps Mediterranean fever, anticorps MEFV, anticorps Mefv

Sujet: This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome.

Poids moléculaire: 86444

NCBI Accession: NP_000234, NP_001185465

UniProt: O15553

Pathways: Positive Regulation of Endopeptidase Activity