MTAP anticorps (N-Term)

N° du produit ABIN1881557

L’anticorps Lapin Polyclonal anti-MTAP a été validé pour WB. Il convient pour détecter MTAP dans des échantillons de Humain. Il y a 3+ publications disponibles.

Aperçu rapide pour MTAP anticorps (N-Term) (ABIN1881557)

Antigène: MTAP (Methylthioadenosine phosphorylase (MTAP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTAP est non-conjugé

Application: Western Blotting (WB)

Clone: RB42759

Détail du produit anti-MTAP anticorps

Épitope: AA 8-37, N-Term

Homologie: B, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MTAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-37 amino acids from the N-terminal region of human MTAP.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-MTAP (ABIN1881557)

Newton-Bishop, Chang, Iles, Taylor, Bakker, Chan, Leake, Karpavicius, Haynes, Fitzgibbon, Elliott, Kanetsky, Harland, Barrett, Bishop: "Melanocytic nevi, nevus genes, and melanoma risk in a large case-control study in the United Kingdom." dans: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 8, pp. 2043-54, (2010) (PubMed).

Zhang, Cheng, Yan, Chen, Wang, Yang: "[Association between methylthioadenosine phosphorylase gene single nucleotide polymorphisms and myocardial infarction in Chinese Han ethnicity]." dans: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, Vol. 31, Issue 1, pp. 83-6, (2010) (PubMed).

Huang, Li, Yu, Chou, Tzeng, Hu, Uen, Tian, Wang, Fang, Huang, Wei, Wu, Li: "Homozygous deletion of MTAP gene as a poor prognosticator in gastrointestinal stromal tumors." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 22, pp. 6963-72, (2009) (PubMed).

Détails sur MTAP

Antigène: MTAP (Methylthioadenosine phosphorylase (MTAP))

Autre désignation: MTAP

Sujet: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.

Poids moléculaire: 31236

NCBI Accession: NP_002442

UniProt: Q13126

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process