Neurogenin 1 anticorps (AA 112-138)

N° du produit ABIN1881577

Cet anticorps Lapin Polyclonal détecte spécifiquement Neurogenin 1 dans WB. Il présente une réactivité envers Poisson zèbre (Danio rerio) et a été mentionné dans 3+ publications.

Aperçu rapide pour Neurogenin 1 anticorps (AA 112-138) (ABIN1881577)

Antigène: Neurogenin 1 (NEUROG1)

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurogenin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Neurogenin 1 anticorps

Épitope: AA 112-138

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This DANRE neurog1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-138 amino acids from the Central region of DANRE neurog1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-Neurogenin 1 (ABIN1881577)

Korzh, Sleptsova, Liao, He, Gong: "Expression of zebrafish bHLH genes ngn1 and nrd defines distinct stages of neural differentiation." dans: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 213, Issue 1, pp. 92-104, (1999) (PubMed).

Kim, Bae, Yamanaka, Yamashita, Shimizu, Fujii, Park, Yeo, Huh, Hibi, Hirano: "Overexpression of neurogenin induces ectopic expression of HuC in zebrafish." dans: Neuroscience letters, Vol. 239, Issue 2-3, pp. 113-6, (1998) (PubMed).

Blader, Fischer, Gradwohl, Guillemot, Strähle: "The activity of neurogenin1 is controlled by local cues in the zebrafish embryo." dans: Development (Cambridge, England), Vol. 124, Issue 22, pp. 4557-69, (1998) (PubMed).

Détails sur Neurogenin 1

Antigène: Neurogenin 1 (NEUROG1)

Autre désignation: neurog1

Sujet: Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon-Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons, involved in the specification of dopaminergic progenitor cells. May be involved in maintaining rhombomere boundaries in the hindbrain.

Poids moléculaire: 22911

NCBI Accession: NP_571116

UniProt: O42606