PTF1A anticorps (N-Term)

N° du produit ABIN1881703

Détail du produit anti-PTF1A anticorps

Antigène: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Épitope: AA 12-43, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTF1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Ptf1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-43 amino acids from the N-terminal region of human Ptf1a.

Clone: RB10418

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-PTF1A (ABIN1881703)

Yamada, Terao, Terashima, Fujiyama, Kawaguchi, Nabeshima, Hoshino: "Origin of climbing fiber neurons and their developmental dependence on Ptf1a." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 41, pp. 10924-34, (2007) (PubMed).

Détails sur PTF1A

Antigène: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Autre désignation: Ptf1a (PTF1A Produits)

Synonymes: anticorps PTF1A, anticorps PTF1, anticorps si:zc142h2.2, anticorps zgc:112216, anticorps Ptf1a/p48, anticorps XPtf1a, anticorps PTF1-p48, anticorps bHLHa29, anticorps PTF1p48, anticorps pancreas specific transcription factor, 1a, anticorps PTF1A, anticorps ptf1a, anticorps Ptf1a

Sujet: Ptf1a is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. This protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in the Ptf1a gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.

Poids moléculaire: 34970

NCBI Accession: NP_835455

UniProt: Q7RTS3

Pathways: Retinoic Acid Receptor Signaling Pathway