PTRH2 anticorps (N-Term)

N° du produit ABIN1881706

Cet anticorps Lapin Polyclonal détecte spécifiquement PTRH2 dans WB. Il présente une réactivité envers Humain et a été mentionné dans 4+ publications.

Aperçu rapide pour PTRH2 anticorps (N-Term) (ABIN1881706)

Antigène: PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTRH2 est non-conjugé

Application: Western Blotting (WB)

Clone: RB42733

Détail du produit anti-PTRH2 anticorps

Épitope: AA 26-55, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PTRH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human PTRH2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-PTRH2 (ABIN1881706)

Fan, Jiang, Suo, Liu, Xu, Ji, Zhang, Yang: "Down-regulation of the apoptosis-inducing factor or Bcl-2 inhibitor of transcription by RNA interference can alleviate TAp63gamma-induced apoptosis in esophageal squamous carcinoma EC9706 cells." dans: International journal of oncology, Vol. 35, Issue 2, pp. 359-67, (2009) (PubMed).

Biliran, Jan, Chen, Pasquale, Ruoslahti: "Protein kinase D is a positive regulator of Bit1 apoptotic function." dans: The Journal of biological chemistry, Vol. 283, Issue 42, pp. 28029-37, (2008) (PubMed).

Bouchentouf, Benabdallah, Rousseau, Schwartz, Tremblay: "Induction of Anoikis following myoblast transplantation into SCID mouse muscles requires the Bit1 and FADD pathways." dans: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 7, Issue 6, pp. 1491-505, (2007) (PubMed).

De Pereda, Waas, Jan, Ruoslahti, Schimmel, Pascual: "Crystal structure of a human peptidyl-tRNA hydrolase reveals a new fold and suggests basis for a bifunctional activity." dans: The Journal of biological chemistry, Vol. 279, Issue 9, pp. 8111-5, (2004) (PubMed).

Détails sur PTRH2

Antigène: PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))

Autre désignation: PTRH2

Sujet: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis (By similarity). Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1.

Poids moléculaire: 19194

NCBI Accession: NP_057161

UniProt: Q9Y3E5