PURA anticorps (C-Term)

N° du produit ABIN1881707

Détail du produit anti-PURA anticorps

Antigène: PURA (Purine-Rich Element Binding Protein A (PURA))

Épitope: AA 259-287, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PURA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PURA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the C-terminal region of human PURA.

Clone: RB20224

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-PURA (ABIN1881707)

Gazla, Carracedo: "Effect of intracellular Wolbachia on interspecific crosses between Drosophila melanogaster and Drosophila simulans." dans: Genetics and molecular research : GMR, Vol. 8, Issue 3, pp. 861-9, (2009) (PubMed).

Kaminski, Darbinyan, Merabova, Deshmane, White, Khalili: "Protective role of Puralpha to cisplatin." dans: Cancer biology & therapy, Vol. 7, Issue 12, pp. 1926-35, (2009) (PubMed).

Martins-de-Souza, Gattaz, Schmitt, Rewerts, Maccarrone, Dias-Neto, Turck: "Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia." dans: European archives of psychiatry and clinical neuroscience, Vol. 259, Issue 3, pp. 151-63, (2009) (PubMed).

Darbinian, Cui, Basile, Del Valle, Otte, Miklossy, Sawaya, Amini, Khalili, Gordon: "Negative regulation of AbetaPP gene expression by pur-alpha." dans: Journal of Alzheimer's disease : JAD, Vol. 15, Issue 1, pp. 71-82, (2008) (PubMed).

Wang, Johnson, Kinoshita, Babb, Buckley, Liebes, Melamed, Liu, Kurek, Ossowski, Ferrari: "Androgen receptor overexpression in prostate cancer linked to Pur alpha loss from a novel repressor complex." dans: Cancer research, Vol. 68, Issue 8, pp. 2678-88, (2008) (PubMed).

Détails sur PURA

Antigène: PURA (Purine-Rich Element Binding Protein A (PURA))

Autre désignation: PURA (PURA Produits)

Synonymes: anticorps CAGER-1, anticorps Pur-alpha, anticorps ssCRE-BP, anticorps PUR-ALPHA, anticorps PUR1, anticorps PURALPHA, anticorps zgc:103411, anticorps pur-alpha, anticorps pur1, anticorps puralpha, anticorps purine-rich element binding protein A, anticorps purine rich element binding protein A, anticorps purine-rich element binding protein Aa, anticorps purine-rich element binding protein A L homeolog, anticorps pura, anticorps Pura, anticorps PURA, anticorps puraa, anticorps pura.L

Sujet: This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Poids moléculaire: 34911

NCBI Accession: NP_005850

UniProt: Q00577