SMAD5 anticorps (AA 241-269)

N° du produit ABIN1881816

Cet anticorps anti-SMAD5 est un anticorps Lapin Polyclonal détectant SMAD5 dans WB. Adapté pour Humain. Ce Primary Antibody a été cité dans 5+ publications.

Aperçu rapide pour SMAD5 anticorps (AA 241-269) (ABIN1881816)

Antigène: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD5 est non-conjugé

Application: Western Blotting (WB)

Clone: RB40948

Détail du produit anti-SMAD5 anticorps

Épitope: AA 241-269

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SMAD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the Central region of human SMAD5.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-SMAD5 (ABIN1881816)

Yang, Li, Al-Lamki, Southwood, Zhao, Lever, Grimminger, Schermuly, Morrell: "Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo." dans: Circulation research, Vol. 107, Issue 2, pp. 252-62, (2010) (PubMed).

Tao, Sampath: "Alternative splicing of SMADs in differentiation and tissue homeostasis." dans: Development, growth & differentiation, Vol. 52, Issue 4, pp. 335-42, (2010) (PubMed).

Park, Lee, Ahn, Kim: "Predicting the multi-modal binding propensity of small molecules: towards an understanding of drug promiscuity." dans: Molecular bioSystems, Vol. 5, Issue 8, pp. 844-53, (2009) (PubMed).

Middlebrook, Eldin, Li, Shivasankaran, Pangas: "Smad1-Smad5 ovarian conditional knockout mice develop a disease profile similar to the juvenile form of human granulosa cell tumors." dans: Endocrinology, Vol. 150, Issue 12, pp. 5208-17, (2009) (PubMed).

Su, Zhu, Han, Feng, Huang, Ren, Pan, Zhang, Lu, Huang: "BMP4-Smad signaling pathway mediates adriamycin-induced premature senescence in lung cancer cells." dans: The Journal of biological chemistry, Vol. 284, Issue 18, pp. 12153-64, (2009) (PubMed).

Détails sur SMAD5

Antigène: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Autre désignation: SMAD5

Sujet: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD).

Poids moléculaire: 52258

NCBI Accession: NP_001001419, NP_001001420, NP_005894

UniProt: Q99717