Syntaxin 11 anticorps (N-Term)

N° du produit ABIN1881853

Cet anticorps Lapin Polyclonal détecte spécifiquement Syntaxin 11 dans WB. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour Syntaxin 11 anticorps (N-Term) (ABIN1881853)

Antigène: Syntaxin 11 (STX11)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Syntaxin 11 est non-conjugé

Application: Western Blotting (WB)

Clone: RB40556

Détail du produit anti-Syntaxin 11 anticorps

Épitope: AA 29-56, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This STX11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-56 amino acids from the N-terminal region of human STX11.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-Syntaxin 11 (ABIN1881853)

Marsh, Satake, Biroschak, Jacobs, Johnson, Jordan, Bleesing, Filipovich, Zhang: "STX11 mutations and clinical phenotypes of familial hemophagocytic lymphohistiocytosis in North America." dans: Pediatric blood & cancer, Vol. 55, Issue 1, pp. 134-40, (2010) (PubMed).

zur Stadt, Rohr, Seifert, Koch, Grieve, Pagel, Strauss, Kasper, Nürnberg, Becker, Maul-Pavicic, Beutel, Janka, Griffiths, Ehl, Hennies: "Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11." dans: American journal of human genetics, Vol. 85, Issue 4, pp. 482-92, (2009) (PubMed).

Marcelin, Diatloff-Zito, Nicole, Robert: "Developmental methylation program and concerted expression of Stx11 in mouse tissues." dans: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 20, Issue 3, pp. 131-9, (2009) (PubMed).

Détails sur Syntaxin 11

Antigène: Syntaxin 11 (STX11)

Autre désignation: STX11

Sujet: This gene encodes a member of the syntaxin family. Syntaxins have been implicated in the targeting and fusion of intracellular transport vesicles. This family member may regulate protein transport among late endosomes and the trans-Golgi network. Mutations in this gene have been associated with familial hemophagocytic lymphohistiocytosis.

Poids moléculaire: 33196

NCBI Accession: NP_003755

UniProt: O75558