TFEC anticorps (AA 179-205)

N° du produit ABIN1881878

L’anticorps Lapin Polyclonal anti-TFEC a été validé pour WB. Il convient pour détecter TFEC dans des échantillons de Humain. Il y a 3+ publications disponibles.

Aperçu rapide pour TFEC anticorps (AA 179-205) (ABIN1881878)

Antigène: TFEC (Transcription Factor EC (TFEC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFEC est non-conjugé

Application: Western Blotting (WB)

Clone: RB40605

Détail du produit anti-TFEC anticorps

Épitope: AA 179-205

Homologie: C, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TFEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-205 amino acids from the Central region of human TFEC.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-TFEC (ABIN1881878)

Mansky, Sulzbacher, Purdom, Nelsen, Hume, Rehli, Ostrowski: "The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter." dans: Journal of leukocyte biology, Vol. 71, Issue 2, pp. 304-10, (2002) (PubMed).

Chung, Kim, Kawamoto: "TFEC can function as a transcriptional activator of the nonmuscle myosin II heavy chain-A gene in transfected cells." dans: Biochemistry, Vol. 40, Issue 30, pp. 8887-97, (2001) (PubMed).

Steingrímsson, Tessarollo, Reid, Jenkins, Copeland: "The bHLH-Zip transcription factor Tfeb is essential for placental vascularization." dans: Development (Cambridge, England), Vol. 125, Issue 23, pp. 4607-16, (1999) (PubMed).

Détails sur TFEC

Antigène: TFEC (Transcription Factor EC (TFEC))

Autre désignation: TFEC

Sujet: Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo-or heterodimeric form.

Poids moléculaire: 38788

NCBI Accession: NP_001018068, NP_001231512, NP_036384

UniProt: O14948