TIPIN anticorps (N-Term)

N° du produit ABIN1881887

L’anticorps Lapin Polyclonal anti-TIPIN a été validé pour WB. Il convient pour détecter TIPIN dans des échantillons de Humain. Il y a 3+ publications disponibles.

Aperçu rapide pour TIPIN anticorps (N-Term) (ABIN1881887)

Antigène: TIPIN (TIMELESS Interacting Protein (TIPIN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIPIN est non-conjugé

Application: Western Blotting (WB)

Clone: RB40607

Détail du produit anti-TIPIN anticorps

Épitope: AA 227-254, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TIPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human TIPIN.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-TIPIN (ABIN1881887)

Kemp, Akan, Yilmaz, Grillo, Smith-Roe, Kang, Cordeiro-Stone, Kaufmann, Abraham, Sancar, Unsal-Kaçmaz: "Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress." dans: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16562-71, (2010) (PubMed).

Leman, Noguchi, Lee, Noguchi: "Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion." dans: Journal of cell science, Vol. 123, Issue Pt 5, pp. 660-70, (2010) (PubMed).

Gotter, Suppa, Emanuel: "Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors." dans: Journal of molecular biology, Vol. 366, Issue 1, pp. 36-52, (2007) (PubMed).

Détails sur TIPIN

Antigène: TIPIN (TIMELESS Interacting Protein (TIPIN))

Autre désignation: TIPIN

Sujet: Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.

Poids moléculaire: 34555

NCBI Accession: NP_060328

UniProt: Q9BVW5