UBE2L3 anticorps (C-Term)

N° du produit ABIN1881966

Cet anticorps anti-UBE2L3 est un anticorps Lapin Polyclonal détectant UBE2L3 dans WB et IHC (p). Adapté pour Humain, Souris et Rat. Ce Primary Antibody a été cité dans 5+ publications.

Aperçu rapide pour UBE2L3 anticorps (C-Term) (ABIN1881966)

Antigène: UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2L3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB41666

Détail du produit anti-UBE2L3 anticorps

Épitope: AA 106-135, C-Term

Homologie: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This UBE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the C-terminal region of human UBE2L3.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-UBE2L3 (ABIN1881966)

Amidon, Hawley: "Oral bioperformance and 21st century dissolution." dans: Molecular pharmaceutics, Vol. 7, Issue 5, pp. 1361, (2013) (PubMed).

Fransen, Visschedijk, van Sommeren, Fu, Franke, Festen, Stokkers, van Bodegraven, Crusius, Hommes, Zanen, de Jong, Wijmenga, van Diemen, Weersma: "Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease." dans: Human molecular genetics, Vol. 19, Issue 17, pp. 3482-8, (2010) (PubMed).

Dubois, Trynka, Franke, Hunt, Romanos, Curtotti, Zhernakova, Heap, Adány, Aromaa, Bardella, van den Berg, Bockett, de la Concha, Dema, Fehrmann, Fernández-Arquero, Fiatal, Grandone, Green, Groen et al.: "Multiple common variants for celiac disease influencing immune gene expression. ..." dans: Nature genetics, Vol. 42, Issue 4, pp. 295-302, (2010) (PubMed).

Kamatani, Matsuda, Okada, Kubo, Hosono, Daigo, Nakamura, Kamatani: "Genome-wide association study of hematological and biochemical traits in a Japanese population." dans: Nature genetics, Vol. 42, Issue 3, pp. 210-5, (2010) (PubMed).

Han, Zheng, Cui, Sun, Ye, Hu, Xu, Cai, Huang, Zhao, Xie, Fang, Lu, Xu, Li, Pan, Deng, Zeng, Ye, Zhang, Wang, Hao, Ma, Zuo, Zhou, Du, Cheng, Yang, Shen, Li, Sheng, Zuo, Zhu, Gao, Zhang, Guo, Li et al.: "Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus...." dans: Nature genetics, Vol. 41, Issue 11, pp. 1234-7, (2009) (PubMed).

Détails sur UBE2L3

Antigène: UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

Autre désignation: UBE2L3

Sujet: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 17862

NCBI Accession: NP_001243284, NP_001243285, NP_003338

UniProt: P68036