ULK2 anticorps (pSer323)

N° du produit ABIN1881982

Cet anticorps Lapin Polyclonal détecte spécifiquement ULK2 dans DB. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour ULK2 anticorps (pSer323) (ABIN1881982)

Antigène: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ULK2 est non-conjugé

Application: Dot Blot (DB)

Clone: RB40763

Détail du produit anti-ULK2 anticorps

Épitope: pSer323

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ULK2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S323 of human ULK2.

Isotype: Ig Fraction

Information d'application

Indications d'application: DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ULK2 (ABIN1881982)

Jung, Jun, Ro, Kim, Otto, Cao, Kundu, Kim: "ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery." dans: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1992-2003, (2009) (PubMed).

Stelzl, Worm, Lalowski, Haenig, Brembeck, Goehler, Stroedicke, Zenkner, Schoenherr, Koeppen, Timm, Mintzlaff, Abraham, Bock, Kietzmann, Goedde, Toksöz, Droege, Krobitsch, Korn, Birchmeier, Lehrach et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." dans: Cell, Vol. 122, Issue 6, pp. 957-68, (2005) (PubMed).

Yan, Kuroyanagi, Tomemori, Okazaki, Asato, Matsuda, Suzuki, Ohshima, Mitani, Masuho, Shirasawa, Muramatsu: "Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains." dans: Oncogene, Vol. 18, Issue 43, pp. 5850-9, (1999) (PubMed).

Détails sur ULK2

Antigène: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Autre désignation: ULK2

Sujet: This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq].

Poids moléculaire: 112694

NCBI Accession: NP_001136082, NP_055498

UniProt: Q8IYT8

Pathways: Regulation of Cell Size, Autophagy