This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This VAPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-210 amino acids from the C-terminal region of human VAPA.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Furuita, Jee, Fukada, Mishima, Kojima: "Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies." dans: The Journal of biological chemistry, Vol. 285, Issue 17, pp. 12961-70, (2010) (PubMed).
Tuuf, Wistbacka, Mattjus: "The glycolipid transfer protein interacts with the vesicle-associated membrane protein-associated protein VAP-A." dans: Biochemical and biophysical research communications, Vol. 388, Issue 2, pp. 395-9, (2009) (PubMed).
Saita, Shirane, Natume, Iemura, Nakayama: "Promotion of neurite extension by protrudin requires its interaction with vesicle-associated membrane protein-associated protein." dans: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13766-77, (2009) (PubMed).
Prosser, Tran, Gougeon, Verly, Ngsee: "FFAT rescues VAPA-mediated inhibition of ER-to-Golgi transport and VAPB-mediated ER aggregation." dans: Journal of cell science, Vol. 121, Issue Pt 18, pp. 3052-61, (2008) (PubMed).
Lohoff, Weller, Bloch, Nall, Ferraro, Berrettini: "Association between polymorphisms in the vesicle-associated membrane protein-associated protein A (VAPA) gene on chromosome 18p and bipolar disorder." dans: Journal of neural transmission (Vienna, Austria : 1996), Vol. 115, Issue 9, pp. 1339-45, (2008) (PubMed).
Antigène
VAPA
(VAMP (Vesicle-Associated Membrane Protein)-Associated Protein A, 33kDa (VAPA))
anticorps VAP-33, anticorps VAP-A, anticorps VAP33, anticorps hVAP-33, anticorps 33kDa, anticorps wu:fa14e12, anticorps zgc:65776, anticorps zgc:77382, anticorps VAMP associated protein A, anticorps vesicle-associated membrane protein, associated protein A, anticorps VAMP (vesicle-associated membrane protein)-associated protein A, anticorps VAPA, anticorps Vapa, anticorps vapa
Sujet
The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.