USP25
Reactivité: Humain
Hôte: Lapin
Polyclonal
FITC
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Groet, Ives, Jones, Danton, Flomen, Sheer, Hrascan, Pavelic, Nizetic: "Narrowing of the region of allelic loss in 21q11-21 in squamous non-small cell lung carcinoma and cloning of a novel ubiquitin-specific protease gene from the deleted segment." dans: Genes, chromosomes & cancer, Vol. 27, Issue 2, pp. 153-61, (2000) (PubMed).
Valero, Marfany, González-Angulo, González-González, Puelles, Gonzàlez-Duarte: "USP25, a novel gene encoding a deubiquitinating enzyme, is located in the gene-poor region 21q11.2." dans: Genomics, Vol. 62, Issue 3, pp. 395-405, (2000) (PubMed).
Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Hydrolyzes both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains.