YARS2 anticorps (C-Term)

N° du produit ABIN1882153

Cet anticorps Lapin Polyclonal détecte spécifiquement YARS2 dans WB et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour YARS2 anticorps (C-Term) (ABIN1882153)

Antigène: YARS2 (Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YARS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB14936

Détail du produit anti-YARS2 anticorps

Épitope: AA 399-427, C-Term

Homologie: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This YARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-427 amino acids from the C-terminal region of human YARS2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-YARS2 (ABIN1882153)

Riley, Menezes, Rudinger-Thirion, Duff, de Lonlay, Rotig, Tchan, Davis, Cooper, Christodoulou: "Phenotypic variability and identification of novel YARS2 mutations in YARS2 mitochondrial myopathy, lactic acidosis and sideroblastic anaemia." dans: Orphanet journal of rare diseases, Vol. 8, pp. 193, (2014) (PubMed).

Riley, Cooper, Hickey, Rudinger-Thirion, McKenzie, Compton, Lim, Thorburn, Ryan, Giegé, Bahlo, Christodoulou: "Mutation of the mitochondrial tyrosyl-tRNA synthetase gene, YARS2, causes myopathy, lactic acidosis, and sideroblastic anemia--MLASA syndrome." dans: American journal of human genetics, Vol. 87, Issue 1, pp. 52-9, (2010) (PubMed).

Bonnefond, Frugier, Touzé, Lorber, Florentz, Giegé, Sauter, Rudinger-Thirion: "Crystal structure of human mitochondrial tyrosyl-tRNA synthetase reveals common and idiosyncratic features." dans: Structure (London, England : 1993), Vol. 15, Issue 11, pp. 1505-16, (2007) (PubMed).

Détails sur YARS2

Antigène: YARS2 (Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))

Autre désignation: YARS2

Sujet: YARS2 catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).

Poids moléculaire: 53199

NCBI Accession: NP_001035526

UniProt: Q9Y2Z4