CDC7 anticorps (N-Term)

N° du produit ABIN1882165

Cet anticorps Lapin Polyclonal détecte spécifiquement CDC7 dans WB. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 3+ publications.

Aperçu rapide pour CDC7 anticorps (N-Term) (ABIN1882165)

Antigène: CDC7 (Cell Division Cycle 7 (CDC7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC7 est non-conjugé

Application: Western Blotting (WB)

Clone: RB3541

Détail du produit anti-CDC7 anticorps

Épitope: AA 1-30, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CDC7 (CDC7L1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CDC7 (CDC7L1).

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-CDC7 (ABIN1882165)

Montagnoli, Bosotti, Villa, Rialland, Brotherton, Mercurio, Berthelsen, Santocanale: "Drf1, a novel regulatory subunit for human Cdc7 kinase." dans: The EMBO journal, Vol. 21, Issue 12, pp. 3171-81, (2002) (PubMed).

Hess, Drong, Weiland, Slightom, Sclafani, Hollingsworth: "A human homolog of the yeast CDC7 gene is overexpressed in some tumors and transformed cell lines." dans: Gene, Vol. 211, Issue 1, pp. 133-40, (1998) (PubMed).

Jiang, Hunter: "Identification and characterization of a human protein kinase related to budding yeast Cdc7p." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 26, pp. 14320-5, (1998) (PubMed).

Détails sur CDC7

Antigène: CDC7 (Cell Division Cycle 7 (CDC7))

Autre désignation: CDC7 (CDC7L1)

Sujet: CDC7L1 is predominantly localized in the nucleus and is a cell division cycle protein with kinase activity. Although expression levels of the protein appear to be constant throughout the cell cycle, the protein kinase activity appears to increase during S phase. It has been suggested that the protein is essential for initiation of DNA replication and that it plays a role in regulating cell cycle progression. Overexpression of this gene product may be associated with neoplastic transformation for some tumors.

Poids moléculaire: 63888

NCBI Accession: NP_001127891, NP_001127892, NP_003494

UniProt: O00311

Pathways: Mitotic G1-G1/S Phases, DNA Replication