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DRD4 anticorps (AA 365-391)

DRD4 Reactivité: Humain, Souris WB Hôte: Souris Monoclonal 625CT1-5-4 unconjugated
N° du produit ABIN1882235
  • Antigène Voir toutes DRD4 Anticorps
    DRD4 (Dopamine Receptor D4 (DRD4))
    Épitope
    • 15
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 365-391
    Reactivité
    • 49
    • 37
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 44
    • 9
    • 1
    Souris
    Clonalité
    • 44
    • 9
    Monoclonal
    Conjugué
    • 28
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DRD4 est non-conjugé
    Application
    • 51
    • 29
    • 13
    • 13
    • 9
    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogène
    This DRD4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from the Central region of human DRD4.
    Clone
    625CT1-5-4
    Isotype
    IgG1
    Top Product
    Discover our top product DRD4 Anticorps primaire
  • Indications d'application
    WB: 1:100~250
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Zeng, Ye, Lu, Chua, Tan, Zhong: "Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes." dans: Organic letters, Vol. 12, Issue 10, pp. 2414-7, (2010) (PubMed).

    Lai, Zhu, Huo, Sun, Yu, Wang, Chai, Li: "Association study of polymorphisms in the promoter region of DRD4 with schizophrenia, depression, and heroin addiction." dans: Brain research, Vol. 1359, pp. 227-32, (2010) (PubMed).

    Gadow, Devincent, Olvet, Pisarevskaya, Hatchwell: "Association of DRD4 polymorphism with severity of oppositional defiant disorder, separation anxiety disorder and repetitive behaviors in children with autism spectrum disorder." dans: The European journal of neuroscience, Vol. 32, Issue 6, pp. 1058-65, (2010) (PubMed).

    Chio, Drong, Riley, Gill, Slightom, Huff: "D4 dopamine receptor-mediated signaling events determined in transfected Chinese hamster ovary cells." dans: The Journal of biological chemistry, Vol. 269, Issue 16, pp. 11813-9, (1994) (PubMed).

  • Antigène
    DRD4 (Dopamine Receptor D4 (DRD4))
    Autre désignation
    DRD4 (DRD4 Produits)
    Synonymes
    anticorps Drd4b, anticorps si:ch211-69h5.1, anticorps zgc:123021, anticorps D4DR, anticorps AW125663, anticorps D4R, anticorps Drd-4, anticorps D4RA, anticorps DRD4, anticorps Drd4c, anticorps dopamine receptor D4 related sequence, anticorps dopamine receptor D4, anticorps dopamine receptor D4b, anticorps drd4-rs, anticorps DRD4, anticorps Drd4, anticorps SRU_2808, anticorps MSMEG_3522, anticorps drd4b
    Sujet
    This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats, the sequence shown contains four repeats.
    Poids moléculaire
    43901
    NCBI Accession
    NP_000788
    UniProt
    P21917
    Pathways
    cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity
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