DC-SIGN/CD209 anticorps (Extracellular Domain)

N° du produit ABIN1885521

Cet anticorps anti-DC-SIGN/CD209 Monoclonal Souris (ABIN1885521) détecte spécifiquement DC-SIGN/CD209 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour DC-SIGN/CD209 anticorps (Extracellular Domain) (ABIN1885521)

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DC-SIGN/CD209 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-DC-SIGN/CD209 anticorps

Épitope: Extracellular Domain

Purification: Immunoaffinity chromotography purified IgG

Immunogène: Raised against a recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN (1).

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: -20 °C

Stockage commentaire: Can be stored at -20 °C, stable for one year.

Date de péremption: 12 months

Détails sur DC-SIGN/CD209

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Autre désignation: DC-SIGN

Sujet: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes , where DCs hand over HIV to CD4+ T lymphocytes.DCs also amplify the amount of virus and extend the duration of viral infectivity.Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN.ICAM-3 is the natural ligand for DC-SIGN.A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently.DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR (8).The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.
Synonyms: DC-SIGN (5D7), Dendritic cell-specific ICAM-3-grabbing nonintegrin 1

UniProt: Q9NNX6