DUSP8 anticorps (AA 1-14)
Aperçu rapide pour DUSP8 anticorps (AA 1-14) (ABIN1885611)
Antigène
Voir toutes DUSP8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-14
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 14 of Human DUSP8
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))
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Autre désignation
- DUSP8
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Sujet
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The protein encoded by this gene is a member of the dualprotein phosphatase subfamily.These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation.Different members of the family of dualphosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin.An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.[provided by RefSeq]
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Poids moléculaire
- 66 kDa
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ID gène
- 1850
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NCBI Accession
- NP_004411, NM_004420
Antigène
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