anticorps MGC64314, anticorps zeh1094, anticorps zgc:85649, anticorps hm:zeh1094, anticorps wu:fa96a09, anticorps wu:fj39g07, anticorps HTF9A, anticorps Htf9a, anticorps RAN binding protein 1 S homeolog, anticorps RAN binding protein 1 L homeolog, anticorps ran binding protein 1, anticorps RAN binding protein 1, anticorps ran-specific GTPase-activating protein pseudogene, anticorps ranbp1.S, anticorps ranbp1.L, anticorps PVX_090070, anticorps GL50803_16969, anticorps LOC100343953, anticorps ranbp1, anticorps RANBP1, anticorps Ranbp1
Sujet
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN.RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP.RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1).The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog.In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.[provided by RefSeq]