EIF4G2 anticorps (AA 1-204)

N° du produit ABIN1885765

Cet anticorps Lapin Polyclonal détecte spécifiquement EIF4G2 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour EIF4G2 anticorps (AA 1-204) (ABIN1885765)

Antigène: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF4G2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-EIF4G2 anticorps

Épitope: AA 1-204

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 204 of Human EIF4G2

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur EIF4G2

Antigène: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Autre désignation: DAP5

Sujet: Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G.The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus.Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes.In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon.Alternatively spliced transcript variants encoding different isoforms of this gene have been described.[provided by RefSeq]

Poids moléculaire: 102 kDa

ID gène: 1982

NCBI Accession: NP_001409, NM_001418