Prosaposin anticorps (AA 1-220)

N° du produit ABIN1885798

Cet anticorps Lapin Polyclonal détecte spécifiquement Prosaposin dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour Prosaposin anticorps (AA 1-220) (ABIN1885798)

Antigène: Prosaposin (PSAP)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prosaposin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Prosaposin anticorps

Épitope: AA 1-220

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 220 of PSAP

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur Prosaposin

Antigène: Prosaposin (PSAP)

Autre désignation: PSAP

Sujet: This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D.Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites.Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups.The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy.Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq]

Poids moléculaire: 58 kDa

ID gène: 5660

NCBI Accession: NP_002769, NM_002778

Pathways: Positive Regulation of Endopeptidase Activity