Factor XI anticorps (AA 1-282)
Aperçu rapide pour Factor XI anticorps (AA 1-282) (ABIN1885884)
Antigène
Voir toutes Factor XI (F11) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-282
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 282 of Human F11
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Factor XI (F11) (Coagulation Factor XI (F11))
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Autre désignation
- Factor XI
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Sujet
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This gene encodes coagulation factor XI of the blood coagulation cascade.This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds.During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds.This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX.Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.[provided by RefSeq]
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Poids moléculaire
- 70 kDa
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ID gène
- 2160
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NCBI Accession
- NP_000119, NM_000128
Antigène
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