TS (AA 122-306) anticorps
Aperçu rapide pour TS (AA 122-306) anticorps (ABIN1885986)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 122-306
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 122 and 306 of human TYMS
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- TS
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Sujet
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Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor.This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair.The enzyme has been of interest as a target for cancer chemotherapeutic agents.It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.[provided by RefSeq]
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Poids moléculaire
- 36 kDa
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ID gène
- 7298
Antigène
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