HSPB8
Reactivité: Humain
WB, IHC, IF, ICC, IP
Hôte: Lapin
Polyclonal
Atto 594
Indications d'application
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.50-1.500 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Agent conservateur
Thimerosal (Merthiolate)
Précaution d'utilisation
Biohazard Informations: This product contains thimerosal which is hazardous.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Antigène
HSPB8
(Heat Shock 22kDa Protein 8 (HSPB8))
Autre désignation
HSPB8
Sujet
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule.The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy.Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.[provided by RefSeq]