HSPB8 anticorps (AA 134-196)
Aperçu rapide pour HSPB8 anticorps (AA 134-196) (ABIN1886015)
Antigène
Voir toutes HSPB8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 134-196
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Synthetic peptide contain a sequence corresponding to a region within amino acids 134 and 196 of HSPB8
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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Autre désignation
- HSPB8
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Sujet
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The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule.The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy.Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.[provided by RefSeq]
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Poids moléculaire
- 22 kDa
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ID gène
- 26353
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NCBI Accession
- NM_014365, NP_055180
Antigène
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