Factor VII anticorps (AA 209-444)

N° du produit ABIN1886186

L’anticorps anti-Factor VII Polyclonal Lapin est utilisé pour la détection de Factor VII dans des échantillons de Humain et Souris. Il a été validé pour WB et IHC.

Aperçu rapide pour Factor VII anticorps (AA 209-444) (ABIN1886186)

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Factor VII est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Factor VII anticorps

Épitope: AA 209-444

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 209 and 444 of Factor VII

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur Factor VII

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Autre désignation: Factor VII

Sujet: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis.This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis.Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond.In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa.Alternative splicing of this gene results in 2 transcripts.Defects in this gene can cause coagulopathy.[provided by RefSeq]

Poids moléculaire: 52 kDa

ID gène: 2155

NCBI Accession: NP_000122, NM_000131

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling