GALR2 anticorps (AA 212-277)

N° du produit ABIN1886197

Cet anticorps Lapin Polyclonal détecte spécifiquement GALR2 dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour GALR2 anticorps (AA 212-277) (ABIN1886197)

Antigène: GALR2 (Galanin Receptor 2 (GALR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GALR2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GALR2 anticorps

Épitope: AA 212-277

Purification: Purified by antigen-affinity chromatography.

Immunogène: Synthetic peptide contain a sequence corresponding to a region within amino acids 212 and 277 of Human GALR2

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur GALR2

Antigène: GALR2 (Galanin Receptor 2 (GALR2))

Autre désignation: galanin receptor 2

Sujet: Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis.It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility.The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors.GALR2 interacts with the N-terminal residues of the galanin peptide.The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi.However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.[provided by RefSeq]

Poids moléculaire: 42 kDa

ID gène: 8811

NCBI Accession: NM_003857, NP_003848

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour