NQO1 anticorps (AA 213-274)
Aperçu rapide pour NQO1 anticorps (AA 213-274) (ABIN1886199)
Antigène
Voir toutes NQO1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 213-274
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Synthetic peptide contain a sequence corresponding to a region within amino acids 213 and 274 of NQO1
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
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Autre désignation
- NQO1
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Sujet
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This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase.This FAD-binding protein forms homodimers and reduces quinones to hydroquinones.This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species.Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer.Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD).Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[provided by RefSeq]
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Poids moléculaire
- 31 kDa
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ID gène
- 1728
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NCBI Accession
- NM_000903, NP_000894
Antigène
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