GAD anticorps (AA 280-582)

N° du produit ABIN1886309

L’anticorps Lapin Polyclonal anti-GAD a été validé pour WB et IF. Il convient pour détecter GAD dans des échantillons de Humain.

Aperçu rapide pour GAD anticorps (AA 280-582) (ABIN1886309)

Antigène: GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAD est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-GAD anticorps

Épitope: AA 280-582

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 280 and 582 of GAD1

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 1 x PBS, 40 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur GAD

Antigène: GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

Autre désignation: GAD67

Sujet: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes.The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid.A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes.This gene may also play a role in the stiff man syndrome.Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures.Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.[provided by RefSeq]

Poids moléculaire: 67 kDa

ID gène: 2571

NCBI Accession: NP_000808, NM_000817