CDC45 anticorps (AA 298-545)

N° du produit ABIN1886335

Cet anticorps Lapin Polyclonal détecte spécifiquement CDC45 dans WB et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CDC45 anticorps (AA 298-545) (ABIN1886335)

Antigène: CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC45 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-CDC45 anticorps

Épitope: AA 298-545

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 298 and 545 of CDC45L

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur CDC45

Antigène: CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))

Autre désignation: CDC45L

Sujet: The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication.Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes.This protein has been shown to interact with MCM7 and DNA polymerase alpha.Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin.Multiple polyadenlyation sites of this gene are reported.[provided by RefSeq]

Poids moléculaire: 66 kDa

ID gène: 8318

NCBI Accession: NP_003495, NM_003504

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA