F10
Reactivité: Humain, Souris, Rat, Chien, Cobaye, Porc, Singe
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.50-1.500 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Agent conservateur
Thimerosal (Merthiolate)
Précaution d'utilisation
Biohazard Informations: This product contains thimerosal which is hazardous.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Antigène
Coagulation Factor X (F10)
Autre désignation
Factor X
Sujet
This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade.This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR.Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases.The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway).The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.[provided by RefSeq]