Coagulation Factor X anticorps (AA 33-282)
Aperçu rapide pour Coagulation Factor X anticorps (AA 33-282) (ABIN1886374)
Antigène
Voir toutes Coagulation Factor X (F10) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 33-282
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 33 and 282 of Human F10
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Coagulation Factor X (F10)
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Autre désignation
- Factor X
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Sujet
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This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade.This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR.Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases.The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway).The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.[provided by RefSeq]
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Poids moléculaire
- 55 kDa
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ID gène
- 2159
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NCBI Accession
- NM_000504, NP_000495
Antigène
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