B-Cell Linker anticorps (AA 394-456)

N° du produit ABIN1886429

L’anticorps Lapin Polyclonal anti-B-Cell Linker a été validé pour WB et IF. Il convient pour détecter B-Cell Linker dans des échantillons de Humain.

Aperçu rapide pour B-Cell Linker anticorps (AA 394-456) (ABIN1886429)

Antigène: B-Cell Linker (BLNK)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp B-Cell Linker est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-B-Cell Linker anticorps

Épitope: AA 394-456

Purification: Purified by antigen-affinity chromatography.

Immunogène: Synthetic peptide contain a sequence corresponding to a region within amino acids 394 and 456 of BLNK

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 1 x PBS, 40 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur B-Cell Linker

Antigène: B-Cell Linker (BLNK)

Autre désignation: B-cell linker protein

Sujet: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development.This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions.The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation.Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked.Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

Poids moléculaire: 50 kDa

ID gène: 29760

NCBI Accession: NP_037446, NM_013314

Pathways: BCR Signaling