GLE1 anticorps (AA 414-656)
Aperçu rapide pour GLE1 anticorps (AA 414-656) (ABIN1886454)
Antigène
Voir toutes GLE1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 414-656
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 414 and 656 of GLE1
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- GLE1 (GLE1 RNA Export Mediator (GLE1))
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Autre désignation
- GLE1
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Sujet
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This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export.Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export.Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes.This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm.Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]
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Poids moléculaire
- 75 kDa
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ID gène
- 2733
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NCBI Accession
- NM_001499, NP_001490
Antigène
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