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GLE1 anticorps (AA 414-656)

Cet anticorps anti-GLE1 est un anticorps Lapin Polyclonal détectant GLE1 dans WB, IHC et IF. Adapté pour Humain.
N° du produit ABIN1886454

Aperçu rapide pour GLE1 anticorps (AA 414-656) (ABIN1886454)

Antigène

Voir toutes GLE1 Anticorps
GLE1 (GLE1 RNA Export Mediator (GLE1))

Reactivité

  • 15
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 13
  • 3
Lapin

Clonalité

  • 15
  • 1
Polyclonal

Conjugué

  • 12
  • 2
  • 1
  • 1
Cet anticorp GLE1 est non-conjugé

Application

  • 11
  • 8
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Épitope

    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 414-656

    Purification

    Purified by antigen-affinity chromatography.

    Immunogène

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 414 and 656 of GLE1
  • Indications d'application

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.500
    Immunofluorescence: 1.100-1.200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    Agent conservateur

    Thimerosal (Merthiolate)

    Précaution d'utilisation

    Biohazard Informations: This product contains thimerosal which is hazardous.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Antigène

    GLE1 (GLE1 RNA Export Mediator (GLE1))

    Autre désignation

    GLE1

    Sujet

    This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export.Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export.Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes.This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm.Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

    Poids moléculaire

    75 kDa

    ID gène

    2733

    NCBI Accession

    NM_001499, NP_001490
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