UNC13(C. Elegans)-Like (AA 462-719) anticorps

N° du produit ABIN1886489

L’anticorps anti-UNC13(C. Elegans)-Like Polyclonal Lapin est utilisé pour la détection de UNC13(C. Elegans)-Like dans des échantillons de Humain. Il a été validé pour IHC et WB.

Aperçu rapide pour UNC13(C. Elegans)-Like (AA 462-719) anticorps (ABIN1886489)

Antigène: UNC13(C. Elegans)-Like

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit

Épitope: AA 462-719

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 462 and 719 of human UNC13B

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détail du antigène

Antigène: UNC13(C. Elegans)-Like

Sujet: This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia.The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain.Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia.Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.[provided by RefSeq]

Poids moléculaire: 181 kDa

ID gène: 10497

NCBI Accession: NP_006368, NM_006377