SAFB anticorps (AA 476-705)
Aperçu rapide pour SAFB anticorps (AA 476-705) (ABIN1886502)
Antigène
Voir toutes SAFB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 476-705
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 476 and 705 of HET/ SAF B
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- SAFB (Scaffold Attachment Factor B (SAFB))
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Autre désignation
- HET/ SAF B
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Sujet
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This gene encodes a DNA-binding protein that has highfor scaffold or matrix attachment region DNA elements (S/MAR DNA).This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein.Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR.This encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes.It is involved in the regulation of the heat shock protein 27 transcription and also can act as an estrogen receptor corepressor.This gene is a candidate gene for breast tumorigenesis.[provided by RefSeq]
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Poids moléculaire
- 103 kDa
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ID gène
- 6294
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NCBI Accession
- NM_002967, NP_002958
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Antigène
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