CKMT1B anticorps (AA 63-297)

N° du produit ABIN1886588

L’anticorps Lapin Polyclonal anti-CKMT1B a été validé pour WB et IHC. Il convient pour détecter CKMT1B dans des échantillons de Humain.

Aperçu rapide pour CKMT1B anticorps (AA 63-297) (ABIN1886588)

Antigène: CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CKMT1B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CKMT1B anticorps

Épitope: AA 63-297

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 63 and 297 of Human CKMT1B

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur CKMT1B

Antigène: CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Autre désignation: Creatine kinase(mitochondrial 1B)

Sujet: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine.It belongs to the creatine kinase isoenzyme family.It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes.Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes.Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis.Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.[provided by RefSeq]
Synonyms: CKMT, CKMT1, UMTCK

Poids moléculaire: 47 kDa

ID gène: 1159

NCBI Accession: NP_066270, NM_020990